Bruker Daltonics ClinProTools Download

The easy-to-use data post-processing software for visualization, data reduction, data mining and building predictive models from protein profiling data using Bruker’s MALDI-TOF mass spectrometers. Supervised classification model generation and validation using different sophisticated mathematical and bioinformatic algorithms. ClinProTools combines intuitive visualization features and multiple mathematical algorithms to generate pattern recognition models for classification and prediction of e.g. disease from mass spectrometry based profiling data. ClinProTools uses a range of algorithms for generating classification models. Genetic Algorithm which mimics evolution in nature, Support Vector Machine motivated from statistical learning theory, Supervised Neural Network (SNN) and QuickClassifier, an univariate sorting algorithm using the p-values at certain peak positions for classification are included. ClinProTools offers various types of result reports to report specific spectra, peak statistic, model, validation or classification data as well as error information.
Correlation Matrix reports are as well available as Model or Validation reports. For increasing the possibilities of biomarker identification and characterization and to complement the Bruker Daltonics biomarker discovery platform a direct link to flexImaging™ software provides comprehensive visualization of the spatial distribution of biomarker candidates in a tissue.
The integration of easy-to-use ClinProTools and flexImaging bioinformatics solutions creates a powerful combination for peak profile classification and MALDI imaging in investigating the distributions of peptides and proteins in tissue samples, known as Class Imaging™ (Patent pending). It allows the classification of tissue types, such as carcinoma, and determination of the class membership of comparable tissues/biopsies.

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